{"id":9635,"date":"2021-07-11T16:57:56","date_gmt":"2021-07-11T21:57:56","guid":{"rendered":"https:\/\/ionicalliance.com\/?p=9635"},"modified":"2021-07-13T16:50:23","modified_gmt":"2021-07-13T21:50:23","slug":"preclinical-antimicrobial-efficacy-studies-on-ibal-formulations","status":"publish","type":"post","link":"https:\/\/ionicalliance.com\/preclinical-antimicrobial-efficacy-studies-on-ibal-formulations\/","title":{"rendered":"Preclinical Antimicrobial Efficacy Studies on IBAL Formulations"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\">Ion Gel ZCM-25 In-vitro Antimicrobial Efficacy Study<\/h2>\n\n\n\n<ul><li>Completed in 2019 by FDA Certified ARJ Labs, Mexico<\/li><li>Ion Gel ZCM-25 had a 100% kill rate in 30 seconds on these human pathogens:<ul><li>Aerobic Mesophilic<\/li><li>Fungi and Yeasts<\/li><li>Staphylococcus Aureus<\/li><li>Pseudomonas Aeruginosa<\/li><\/ul><\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">ION-ZCM1 Redox Potential Assay<\/h2>\n\n\n\n<ul><li>Completed in 2018 by Exova, USA<\/li><li>Oxidation-Reduction Potential was measured at 453.2 mV using method SM2580B<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">ION-ZC1 Redox Potential Assay<\/h2>\n\n\n\n<ul><li>Completed in 2018 by Exova, USA<\/li><li>Oxidation-Reduction Potential was measured at 532.1 mV using method SM2580B<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Ion-ZCM1 Oxygen Radical Absorbance Capacity ORAC Activity Assay<\/h2>\n\n\n\n<ul><li>Completed in 2018 by the University of Debrecen, Hungary<\/li><li>ION-ZCM1 has a TOTAL ORAC = H-ORAC value of 1138 \u03bcM TE \/100 g<\/li><li>Total ORAC value for ION-ZCM1 is 1025 \u03bcM TE\/ml when measured at a dilution of 12.5%<\/li><li>Total ORAC value for ION-ZCM1 is 740 \u03bcM TE\/ml when measured at a dilution of 6.25%<\/li><li>Total ORAC value for Vitamin E is 580 to 585 \u03bcmol TE\/g at 1:1<\/li><li>Total ORAC value for Vitamin C is 128 to 133 \u03bcmol TE\/g at 1:1<\/li><li>Total ORAC value for Pepper Leaf Extract is 64.47 \u03bcmol TE\/g at 1:50 or approx a 2% solution<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">ION-ZC1 In Vitro Antimicrobial Study On 12 Hospital Acquired Pathogens Gram-Negative And Gram-Positive Bacterias And Fungus<\/h2>\n\n\n\n<ul><li>Completed in 2016 by the University of Debrecen, Hungary<\/li><li>A non-biofilm antimicrobial assays using broth microdilution-based sensitivity method.<\/li><li>All fungal and bacterial strains tested with ION-ZC1 concentrations below 2.125 % v\/v observed a 50% turbidity within the 24-hour testing period.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">ION-ZC1 In Vitro Antimicrobial Study On MRSA<\/h2>\n\n\n\n<ul><li>Completed in 2017 by the University of Debrecen, Hungary<\/li><li>A non-biofilm antimicrobial assays using broth microdilution-based sensitivity method.<\/li><li>The results showed that MIC values for ION-ZC1 against the 10-methicillin-resistant Staphylococcus aureus isolate tested were in the range of 0.212 \u2013 0.85% (v\/v).<\/li><li>The Control for Vancomycin, MIC values were in the range of 4-16 mg\/L.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">ION-ZC1 In Vitro Antimicrobial Study On Biofilm<\/h2>\n\n\n\n<ul><li>Completed in 2018 by the University of Debrecen, Hungary<\/li><li>An antimicrobial assays using a microtiter dish sensitivity method.<\/li><li>Minimum inhibitory concentrations (MICs) were determined after 24 hours at which a prominent decrease of 50% (average) of biofilm mass was observed over 36 isolates.<\/li><\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Ion Gel ZCM-25 In-vitro Antimicrobial Efficacy Study Completed in 2019 by FDA Certified ARJ Labs, Mexico [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":8977,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false,"footnotes":""},"categories":[31,64,19],"tags":[],"_links":{"self":[{"href":"https:\/\/ionicalliance.com\/wp-json\/wp\/v2\/posts\/9635"}],"collection":[{"href":"https:\/\/ionicalliance.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ionicalliance.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ionicalliance.com\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/ionicalliance.com\/wp-json\/wp\/v2\/comments?post=9635"}],"version-history":[{"count":0,"href":"https:\/\/ionicalliance.com\/wp-json\/wp\/v2\/posts\/9635\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ionicalliance.com\/wp-json\/wp\/v2\/media\/8977"}],"wp:attachment":[{"href":"https:\/\/ionicalliance.com\/wp-json\/wp\/v2\/media?parent=9635"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ionicalliance.com\/wp-json\/wp\/v2\/categories?post=9635"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ionicalliance.com\/wp-json\/wp\/v2\/tags?post=9635"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}